dr Bato M. Korać

Lični podaci

Obrazovanje: Diploma 1988 Univerzitet u Beogradu, Prirodno-matematički fakultet, Molekularna biologija i fiziologija, Srbija; Magistratura 1991 Univerzitet u Beogradu, Biološki fakultet, Molekularna biologija i fiziologija, Srbija; Doktorat 1996 Univerzitet u Beogradu, Biološki fakultet, Molekularna biologija i fiziologija, Srbija.

Obrazovanje i usavršavanja

1982-1988: Osnovne studije - Biološke nauke / Univerzitet u Beogradu - Biološki fakultet (Beograd)

1989-1991: Magistratura - Biološke nauke / Univerzitet u Beogradu - Biološki fakultet (Beograd)

1996: Doktorat - Biološke nauke / Univerzitet u Beogradu - Biološki fakultet (Beograd)

Kretanje u službi

2004: Vanredni profesor / Univerzitet u Beogradu - Biološki fakultet (Beograd)

Oblasti naučnog interesovanja

Molekularna biologija, biohemija i fiziologija, sa posebnim osvrtom na redoks regulaciju fundamentalnih ćelijskih procesa (proliferacija, hiperplazija, angiogeneza, mitohondriogeneza) u patološkim i fiziološkim stanjima, kao i tokom prilagođavanja specifičnim uslovima sredine (hibernacija). Centralni interes je ispitivanje mehanizmima delovanja reaktivnih vrsti kiseonika i azota, sa fokusom istraživanja na redoks-senzitivne molekule i procese i redok senzitivne transkripcione faktore, posebno u pogledu mogućnosti modulacije redoks-statusa ćelija u terapeutske svrhe i lečenja ozbiljnih metaboličkih poremećaja, metaboličkog sindroma, gojaznosti, dijabetesa, kardiovaskularnih i neurodegenerativnih oboljenja i muškog steriliteta.

Ostale aktivnosti

Član sledećih naučnih društava:

• Društvo za neuronauke Srbije.
• Physiological Society.
• Society for Free Radical Research - Europe.
• Federation of European Neuroscience Societies (FENS).
• Srpsko društvo za mitohondrijalnu i slobodno-radikalsku fiziologiju. Predsednik i jedan od osnivača Društva
• Društvo za ishranu Srbije.
• Srpsko udruženje za upotrebu životinja u istraživanju i obrazovanju. Predsednik Etičkog komiteta Udruženja
• European Association for the Study of Diabetes..

Kretanje u službi:

• 2007. - Naučni savetnik, Univerzitet u Beogradu, Institut za biološka istraživanja "Siniša Stanković", Srbija;
• 2009. - Vanredni profesor, Univerzitet u Beogradu, Biološki fakultet, Srbija.

Nacionalni istraživački projekti:

• Belo ili/i mrko: značaj masnog tkiva u održanju ukupne redoks zavisne metaboličke kontrole u fiziološkim adaptacijama i metaboličkim poremećajima.
• Uloga reaktivnih vrsta kiseonika i azota u reprodukciji: moguća primena u lečenju humanog steriliteta.

Angažman u nastavi

• Fiziologija (063B2)

Brojevi za identifikaciju autora

• Scopus:   7004439177

Izabrane reference

20 selected publications:

1. Jankovic A, Korac A, Srdic-Galic B, Buzadzic B, Otasevic V, Stancic A, Vucetic M, Markelic M, Velickovic K, Golic I, and Korac B. (2014) Differences in the redox status of human visceral and subcutaneous adipose tissues - relationships to obesity and metabolic risk. Metabolism: Clinical and Experimental, 63: 661-671.
2. Buzadzic B, Vucetic M, Jankovic A, Stancic A, Korac A, Korac B, and Otasevic V. (2014) New insights into male (in)fertility: The importance of NO. Br. J. Pharmacol., doi: 10.1111/bph.12675.
3. Otasevic V, Surlan L, Vucetic M, Tulic I, Buzadzic B, Stancic A, Jankovic A, Velickovic K, Golic I, Markelic M, Korac A, and Korac B. (2014)  Different expression patterns of mitochondrial OXPHOS components and mitofusin 1/dynamin related protein 1 is associated with human embryo fragmentation. Reproduction, Fertility and Development, http://dx.doi.org/10.1071/RD13415.
4. Velickovic K, Cvoro A, Srdic B, Stokic E, Markelic M, Golic I, Otasevic V, Stancic A, Jankovic A, Vucetic M, Buzadzic B, Korac B, and Korac A. (2014) Expression and Subcellular Localization of Estrogen Receptors α and β in Human Fetal Brown Adipose Tissue. J Clin Endocrinol Metab., 99: 151-159.
5. Vučetić M., Stančić A., Otašević V., Janković A., Korać A., Markelić M., Veličković K., Golić I., Buzadžić B., Storey B.K. and Korać B. (2013) The impact of cold acclimation and hibernation on antioxidant defenses in the ground squirrel (Spermophilus citellus): An update. Free Radic. Biol. Med., 65: 916-924.
6. Jankovic A, Korac A, Buzadzic B, Otasevic V, Stancic A, Vucetic M, Markelic M, Velickovic K, Golic I, and Korac B. (2013) Endocrine and Metabolic Signaling in Retroperitoneal White Adipose Tissue Remodeling during Cold Acclimation. J. Obes., http://dx.doi.org/10.1155/2013/937572.
7. Stančić A, Otašević V, Janković A, Vučetić M, Ivanović-Burmazović I, Filipović RM, Korać A, Markelić M, Veličković K, Golić I, Buzadžić B, and Korać B. (2013) Molecular basis of hippocampal energy metabolism in diabetic rats: The effects of SOD mimic. Brain Res Bull., 99: 27-33.
8. Otašević V., Korać A., Vučetić M., Macanović B., Garalejić E., Ivanović-Burmazović I., Filipović MR., Buzadžić B., Stančić A., Janković A., Veličković K., Golić I., Markelić M. and Korać B. (2013) Is Manganese (II) Pentaazamacrocyclic Superoxide Dismutase Mimic Beneficial for Human Sperm Mitochondria Function and Motility? Antioxid. Redox Signal., 18: 170-178.
9. Velickovic K, Markelic M, Golic I, Otasevic V, Stancic A, Jankovic A, Vucetic M, Buzadzic B, Korac B, and Korac A. (2013) Long-term dietary L-arginine supplementation increases endothelial nitric oxide synthase and vasoactive intestinal peptide immunoexpression in rat small intestine. Eur. J. Nutr., doi:10.1007/s00394-013-0585-8.
10. Stancic A, Buzadzic B, Korac A, Otasevic V, Jankovic A, Vucetic M, Markelic M, Velickovic K, Golic I, and Korać B. (2013) Regulatory role of PGC-1 alpha/PPAR signaling in skeletal muscle metabolic recruitment during cold acclimation. J Exp. Biol., 216: 4233-4241.
11. Stančić A., Korać A., Buzadžić B., Otašević V., Janković A., Vučetić M. and Korać B. (2012) L-Arginine in Nutrition: Multiple Beneficial Effects in the Etiopathology of Diabetes. J. Nutritional Therapeutics, 1: 114-131.
12. Jović M., Stančić A., Nenadić D., Cekić O., Nezić D., Milojević P., Micović S., Buzadžić B., Korać A., Otašević V., Janković A., Vučetić M., Veličković K., Golić I. and Korać B. (2012) Mitochondrial molecular basis of sevoflurane and propofol cardioprotection in patients undergoing aortic valve replacement with cardiopulmonary bypass. Cell. Physiol. Biochem., 29: 131-142.
13. Vučetić M., Otašević V., Korać A., Stančić A., Janković A., Markelić M., Golić I., Veličković K., Buzadžić B. and Korać B. (2011) Interscapular brown adipose tissue metabolic reprogramming during cold acclimation: Interplay of HIF-1α and AMPKα. Biochim. Biophys. Acta, 1810:1252-1261.
14. Otašević V., Korać A., Buzadžić B., Stančić A., Janković A. and Korać B. (2011) Nitric oxide and thermogenesis - challenge in molecular cell physiology. Frontiers Biosci., 3: 1180-1195.
15. Petrović V., Buzadžić B., Korać A., Vasilijević A., Janković A. and Korać B. (2010) NO modulates the molecular basis of rat interscapular brown adipose tissue thermogenesis. Comp. Biochem. Physiol. C, 152: 147-159.
16. Petrović V., Buzadžić B., Korać A., Vasilijević A., Janković A. and Korać B. (2009) L-arginine supplementation induces glutathione synthesis in interscapular brown adipose tissue through activation of glutamate-cysteine ligase expression: The role of nitric oxide. Chem. Biol. Interact., 182: 204-212.
17. Korać A., Buzadžić B., Petrović V., Vasilijević A., Janković A. and Korać B. (2008). The role of nitric oxide in remodeling of capillary network in rat interscapular brown adipose tissue after long-term cold acclimation. Histol. Histopathol., 23, 441-450.
18. Petrović V., Korać A., Buzadžić B., Vasilijević A., Janković A., Mićunović K. and Korać B. (2008). Nitric oxide regulates mitochondrial re-modeling in interscapular brown adipose tissue: ultrastructural and morphometric-stereologic studies. J. Microsc., 232, 542-548.
19. Vasilijević A., Buzadžić B., Korać A., Petrović V., Janković A. and Korać B. (2007). Beneficial effects of L-arginine-nitric oxide-producing pathway in rats treated with alloxan. J. Physiol., 584, 921-933.
20. Petrović V., Buzadžić B., Korać A., Vasilijević A., Janković A. and Korać B. (2006). Free radical equilibrium in interscapular brown adipose tissue: relationship between metabolic profile and antioxidative defense. Comp. Biochem. Physiol. C, 142, 60-65.