[dr Deana B. Andric]

Хемијски факултет, Студентски трг 12-16, Београд
Катедра за органску хемију

Телефон:   011-3336759

Телефон (локални):   759

Кабинет:   476

Лабораторија:   463

E-mail:   deanad@chem.bg.ac.rs

Лични подаци

Датум и место рођења: 20. 1. 1963, Београд. Удата. Језици које користи: српски (матерњи) и енглески.

Образовање и усавршавања

1981-1987: Основне студије - Хемијске науке / Природно-математички факултет (Београд)

1987-1991: Магистратура - Хемијске науке / Универзитет у Београду - Хемијски факултет (Београд)

1992-1996: Докторат - Хемијске науке / Универзитет у Београду - Хемијски факултет (Београд)

Кретање у служби

1989-1991: Сарадник и настави / ИХТМ (Београд)

1991-1999: Асистент / Ветеринарски факултет (Београд)

1999-2010: Доцент / Универзитет у Београду - Хемијски факултет (Београд)

2010-2024: Ванредни професор / Универзитет у Београду - Хемијски факултет (Београд)

2024: Редовни професор / Универзитет у Београду - Хемијски факултет (Београд)

Области научног интересовања

Медицинска хемија - синтеза и испитивање допаминергичке и серотонергичке активности синтетисаних лиганада и компјутерско моделовање интеракција лиганд-рецептор

Остале активности

Члан Српског хемијског друштва од 1. 1. 1989. - Секција за медицинску хемију; Секција за органску хемију.

Продекан за финансије Хемијског факултета од 19. 5. 2007. до 19. 5. 2010.

Председник Комисије за дисциплинску одговорност студената од 12. 7. 2021.

Заменик председника Етичке комисије од 9. 11. 2023.

Ангажман у настави

Учешће у научноистраживачким пројектима

Завршени пројекти:

  • 2011: Проучавање односа структуре и активности новосинтетисаних биолошки активних супстанци – 172032
    врста пројекта:   домаћи фундаментални
    пројекат финансира:   Министарство за науку и технолошки развој Републике Србије (Београд)

Бројеви за идентификацију аутора

Изабране референце

Књиге и ревијални радови / Books and reviews:

  1. Prof. dr Danica Katanić, doc. dr Deana Dragović, asis. mr Iris Đorđević: Praktikum iz hemije sa računskim zadacima/Fakultet veterinarske medicine, Univerzitet u Beogradu, Beograd 1999./
  2. Dr Deana Andrić, dr Goran Roglić: Radni listovi iz organske hemije/Hemijski fakultet Univerzitet u Beogradu, Beograd 2010./
  3. Deana B. Andrić, Vladimir B. Šukalović: Piperazin - magičan molekul/Univerzitet u Beogradu - Hemijski fakultet , Beograd 2024./

Изабрани радови / Selected papers:

  1. Roglić, Goran; Andrić, Deana; Kostić-Rajačić, Slađana; Dukić, Slađana; Šoškić, Vukić: Introduction of a methyl group in α- or β- position of 1-heteroarylethyl-4-phenylpiperazines affects their dopaminergic/serotonergic properties. Arch. Pharm. (2001), 334, 373-378.
  2. Roglić Goran; Dukić-Stefanović, Slađana; Andrić, Deana; Kostić-Rajačić, Slađana; Šoškić, Vukić: Investigation of mixed D2/5-HT1A activity of N-heteroarylmethyl-N-phenylpiperazines, N-heteroarylethyl-N-phenylpiperazines and N-heteroarylpropyl-N-phenylpiperazines. Pharmazie (2001), 56, 803-807.
  3. Šukalović, Vladimir; Roglić, Goran; Husinec, Suren; Kostić-Rajačić, Slađana; Andrić, Deana; Šoškić, Vukić: D2 dopaminergic 5HT1A serotonergic activity of 2-(1-naphtyl)ethyl- and 2-(2-naphtyl)ethyl amines. Arch. Pharm. (2003), 336, 514-522.
  4. Tomić, Mirko; Kundaković, Marija; Butorović, Biljana; Vasilev, Vesna; Dragović, Deana; Roglić, Goran; Ignjatović, Đurđica; Šoškić, Vukić; Kostić-Rajačić, Slađana: Pharmacological evaluation of 5-(2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl)-1,3-dihydro-benzimidazole-2-thione as a potential atypical antipsychotic agent. Pharmazie (2003), 58, 677-678.
  5. Šukalović, Vladimir; Andrić, Deana; Kostić Rajačić, Slađana; Roglić Goran; Šoškić, Vukić: Electrostatic surface potential calculation on several new halogenated benzimidazole-like dopaminergic ligands. Arch. Pharm. (2004), 337, 376-382.
  6. Šukalović, Vladimir; Zlatović Mario; Andrić, Deana; Kostić-Rajačić, Slađana; Roglić, Goran; Šoškić, Vukić: Modeling of the D2 dopamine receptor arylpiperazine binding site for 1-(2-[5-(1/H/-benzimidazole-2-thione)]ethyl)-4-arylpiperazines. Arch. Pharm. (2004), 337, 502-512.
  7. Veličković, Jelena; Andrić, Deana; Roglić, Goran; Tešić, Živoslav; Milojković-Opsenica, Dušanka: Planar chromatography of some 1-arylpiperazines behaving as dopaminergic ligands. JPC-J. Planar. Chromat. (2004), 17, 255-260.
  8. Tomić, Mirko; Kundaković, Marija; Butorović, Biljana; Janać, Branka; Andrić, Deana; Roglić, Goran; Ignjatović, Đurđica; Kostić-Rajačić, Slađana: Pharmacological evaluation of selected arylpiperazines with atypicalantipsychotic potential. Bioorg. Med. Chem. Lett. (2004), 14, 4263-4266.
  9. Šukalović, Vladimir; Andrić, Deana; Roglić, Goran; Kostić-Rajačić, Slađana; Schrattenholz, Andreas; Šoškić, Vukić: Synthesis, dopamine D2 receptor binding studies and docking analysis of 5-3-(4-arylpiperazin-1-yl)propyl-1H-benzimidazole, 5-2-(4-arylpiperazin-1-yl)ethoxy-1H-benzimidazole and their analogues. Eur. J. Med. Chem. (2005), 40, 481-493.
  10. Šukalović, Vladimir; Zlatović Mario; Andrić, Deana; Roglić, Goran; Kostić-Rajačić, Slađana; Šoškić, Vukić: Interaction of arylpiperazines with the D2 dopamine receptor binding site. Arzneimittel-Forsch./Drug Res. (2005), 55, 145-152.
  11. Zlatović Mario; Šukalović, Vladimir; Kostić-Rajačić, Slađana; Andrić, Deana; Roglić, Goran: Influence of N-1 substituent properties on binding affinities of arylpiperazines to the binding site of 5-HT1A receptor. J.Serb.Chem.Soc. (2006), 71(11), 1125-1135.
  12. Andrić, Deana; Tovilović, Gordana; Roglić, Goran; Vasković, Đurđica; Šoškić, Vukić; Tomić, Mirko; Kostić-Rajačić, Slađana: Synthesis and pharmacological evaluation of several N-(2-nitrophenyl)piperazine derivatives. J.Serb.Chem.Soc. (2007),72(5), 429-435.
  13. Andrić, Deana; Tovilović, Gordana; Roglić, Goran; Šoškić, Vukić, Tomić, Mirko; Kostić-Rajačić, Slađana: 6-[2-(4-Arylpiperazin-1-yl)ethyl]-4-halo-1,3-dihydro-2H-benzimidazole-2-thiones: synthesis and pharmacological evaluation. J.Serb.Chem.Soc. (2007), 72(8-9), 747-755.
  14. Penjišević, Jelena; Šukalović, Vladimir; Andrić, Deana; Kostić-Rajačić, Slađana; Šoškić, Vukić; Roglić, Goran: 1-Cinnamyl-4-(2-methoxyphenyl)piperazines: synthesis, binding properties, and docking to dopamine (D2) and serotonin (5-HT1A) receptors. Arch. Pharm. Chem. Life Sci. (2007), 340, 456-465.
  15. Tomić, Mirko; Ignjatović, Đurđica; Tovilović, Gordana; Andrić, Deana; Roglić, Goran; Kostić-Rajačić, Slađana: Two new phenylpiperazines with atypical antipsychotic potential. Bioorg. Med. Chem. Lett. (2007), 17, 5749-5753.
  16. Andrić, Deana; Roglić, Goran; Šukalović, Vladimir; Šoškić, Vukić; Kostić-Rajačić, Slađana: Synthesis, binding properties and receptor docking of 4-halo-6-[2-(4-arylpiperazin-1-yl)ethyl]-1H-benzimidazoles, mixed ligands of D2- and 5-HT1A receptors. Eur. J. Med. Chem. (2008), 43, 1696-1705.
  17. Šukalović, Vladimir; Zlatović, Mario; Roglić, Goran; Kostić-Rajačić, Slađana; Andrić, Deana: Application of hybrid density functional theory in calculation edge-to-face interactions of receptor-ligand system. Acta. Chim. Slov. (2009), 56, 270-277.
  18. Trfković, Jelena; Andrić, Filip; Ristivojević, P.; Andrić, Deana; Tešić, Živoslav; Milojković-Opsenica, Dušanka: Structure-retention relationship studz of arylpiperazines by linear multivariate modeling. J. Sep. Sci. (2010), 33, 2619-2628.
  19. Tomić, Mirko; Vasković, Đurđica; Tovilović, Gordana; Andrić, Deana; Penjišević, Jelena; Kostić-Rajačić, Slađana: Pharmacological evaluation of halogenated and non-halogenated arylpiperazin-1-yl-ethyl-benzimidazoles as D2 and 5-HT2A receptor ligands. Arch. Pharm. Chem. Life Sci. (2011), 344(5), 287-291.
  20. Senćanski, Milan; Šukalović, Vladimir; Došen-Mićović, Ljiljana; Šoškić, Vukić; Andrić, Deana; Roglić, Goran; Kostić-Rajačić, Slađana: Modeling interactions of alpha (1a) adenergic receptor and different arylpiperazine ligands. Dig. J. Nanomater. Bios. (2012), 7(4), 1767-1777.
  21. Šukalović, Vladimir; Ignjatović, Đurđica; Tovilović, Gordana; Andrić, Deana; Shakib, K.; Kostić-Rajačić, Slađana; Vukić, Šoškić: Interactions of N-{[2-(4-phenyl-piperazin-1-yl)-ethyl]-phenyl}-2-aryl-2-yl-acetamides and 1-{[2-(4-phenyl-piperazin-1-yl)-ethyl]-phenyl}-3-aryl-2-yl-ureas with dopamine D2 and 5-hydroxyltryptamine 5HT1A receptors. Bioorg. Med. Chem. Lett. (2012), 22(12), 3967-3972.
  22. Ignjatović, Đurđica; Vojnović Milutinović, D.; Nikolić-Kokić, A.; Slavić, M.; Andrić, Deana; Tomić, Mirko; Kostić-Rajačić, Slađana: The mechanisms responsible for neuroprotective capacity of arylpiperazine dopaminergic ligands against cell death induced by sodium nitroprusside. Eur. J. Pharmacol. (2012), 683, 93-100.
  23. Šulalović, Vladimir; Šoškić, Vukić; Andrić, Deana, Roglić, Goran; Kostić-Rajačić, Slađana: Modeling key interactions between dopamine D2 receptor second extracellular loop and arylpiperazine ligands. J. Serb. Chem. Soc. (2012), 77(3), 259-277.
  24. Novaković, Irena; Penjišević, Jelena; Šukalović, Vladimir; Andrić, Deana; Roglić, Goran; Kostić-Rajačić, Slađana: Investigation of antibacterial activity of cinnamyl derivates of arylpiperazine. Arch. Biol. Sci. (2012), 64(1), 15-20.
  25. Šukalović, Vladimir; Bogdan, A.E.; Tovilović, Gordana; Ignjatović, Đurđica; Andrić, Deana; Kostić-Rajačić, Slađana; Šoškić, Vukić: N-{[2-(4-Phenyl-piperazin-1-yl)-ethyl]-phenyl}-arylamides with dopamine D2 and 5-hydroxytryptamine 5HT1A activity: synthesis, testing and molecular modeling. Arch. Pharm. Chem. Life Sci. (2013), 346, 708-717.
  26. Šukalović, Vladimir; Šiškić, Vukić; Senćanski, Milan; Andrić, Deana; Kostić-Rajačić, Slađana: Determination of key receptor-ligand interactions of dopaminergic arylpiperazines and the dopamine D2 receptor homology model. J. Mol. Model. (2013), 19(4), 1751-1762.
  27. Vasić, Vesna; Penjišević, Jelena; Novaković, Irena; Šukalović, Vladimir; Andrić, Deana; Kostić-Rajačić, Slađana: Synthesis and biological evaluation of 5-substituted derivatives of benzimidazole. J. Serb. Chem. Soc. (2014), 79(3), 277-282.
  28. Šukalović, Vladimir; Šoškić, Vukić; Ignjatović, Đurđica; Andrić, Deana; Penjišević, Jelena; Kostić-Rajačić, Slađana: Investigation of key interactions between the second extracellular loop of the dopamine D2 receptor and several hydroxy-N-{[2-(4-phenylpiperazin-1-yl)ethyl]phenyl}-nicotinamides. J. Serb. Chem. Soc. (2014), 79(12), 1461-1467.
  29. Penjišević, Jelena; Šukalović, Vladimir; Andrić, Deana; Roglić, Goran; Šoškić, Vukić; Kostić-Rajačić, Slađana: Synthesis, biological, and Computational evaluation of substituted 1-(2-methoxyphenyl)-4-(1-phenethylpiperidin-4-yl)piperazines and 1-(2-methoxyphenyl)-4-[(1-phenethylpiperidin-4-yl)methyl]piperazines as dopaminergic ligands. Arch. Pharm. Chem. Life Sci. (2016), 349, 614-626.
  30. Kostić-Rajačić, Slađana; Schwall, Gerhart; Penjišević, Jelena; Andrić, Deana; Šukalović, Vladimir;  Šoškić, Vukić: Identification of NQO1 and ferrochelatase as interaction partners for neuroprotective N-{[2-(4-phenylpiperazin-1-yl)ethyl]phenyl}arylamides. Chem. Biol. Drug Des. (2018), 91(1), 1393-1397.
  31. Šegan, Sandra; Penjišević, Jelena; Šukalović, Vladimir; Andrić, Deana; MIlojković-Opsenica, Dušanka: Investigation of lipophilicity and pharmacokinetic properties of 2-(methoxyphe nyl)piperazine dopamine D2 ligands. J. Chromatogr. B (2019), 1124, 146-153.
  32. Jevtić, Ivana; Lai, Hang; Penjišević, Jelena; Dukić-Stefanović, Slađana; Andrić, Deana; Burst, Peter; Kostić-Rajačić, Slađana; Teodoro, Rodrigo: Newly synthesized fluorinated cinnamylpiperazines possessing low in vitro MAO-B binding. Molecules (2020), 25(21), 4941.
  33. Dukić-Stefanović, Slađana; Lai, Hang; Toussaint, Magali; Claus, Oliver; Jevtić, Ivana; Penjišević, Jelena; Andrić, Deana; Ludwig, Freidrich-Alexander; Gundel, Daniel; Deuther-Conrad, Winnie; Kostić-Rajačić, Slađana; Burst, Peter; Teodoro, Rodrigo: In vitro and in vivo evaluation of fluorinated indanone derivatives as potential positron emission tomography agents for the imaging of monoamine oxidase B in the brain. Bioorg. Med. Chem. Lett. (2021), 48, 128254.
  34. Penjišević, Jelena; Šukalović, Vladimir; Andrić, Deana; Suručić, Relja; Kostić-Rajačić, Slađana: The therapeutic potential of 2-{[4-(2-methoxyphenyl)piperazin-1-yl]alkyl}-1H-benzo[d]imi dazoles as ligands for alpha1-adrenergic receptor-comparative in silico and in vitro study. App. Biochem. Biotechnol. (2022), 194(8), 3749-3764.
  35. Penjišević, Jelena; Šukalović, Vladimir; Dukić-Stefanović, Slađana; Deuther-Conrad, Winnie; Andrić, Deana; Kostić-Rajačić, Slađana: Synthesis of novel 5-HT1A arylpiperazine ligands: binding data and computer-aided analysis of pharmacological potency. Arab. J. Chem. (2023), 16, 104636.
  36. Jevtić, Ivana; Suručić, Relja; Tovilović, Gordana; Zogović, Nevena; Kostić, Rajačić, Slađana; Andrić, Deana; Penjišević, Jelena: Multi-Target potential of newly designed tacrine-derived choline sterase inhibitors: synthesis, computational and pharmacological study. Bioorg. Med. Chem. (2024) 101, 117649.