Group Members

  • Milan Nikolić, PhD - Associate Professor, University of Belgrade - Faculty of Chemistry
  • Simeon Minić, PhD - Assistant Professor/Senior Research Associate, University of Belgrade - Faculty of Chemistry
  • Luka Veličković - PhD student (Biochemistry), University of Belgrade - Faculty of Chemistry (GFI project)
  • Lora Tubić -(PhD student (Biochemistry), University of Belgrade - Faculty of Chemistry)
  • Zorana Jovanović - PhD student (Chemistry), University of Belgrade - Faculty of Chemistry (ANSO project)
  • dr Srđan Stojanović - Principal Research Fellow, ICTM - Center for Chemistry
  • dr Nikola Gligorijević - Senior Research Associate, ICTM - Center for Chemistry (ANSO project)

Research Areas

  • color stabilization of algal phycobiliproteins for use in the food industry
  • bioactive potential (chromo)peptides from food
  • studies of the effects of phycobilin chromophores binding to blood proteins and DNA/RNA
  • effects of selected drugs (different classes of psychopharmaceuticals) on human blood proteins and erythrocytes
  • Bioinformatics analysis of the stability of selected proteins
  • Development of algal-based products as cell media components for meat cultivation

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Selected Publications

  • Veličković L, Simović A, Gligorijević N, Thureau A, Obradović M, Vasović T, Sotiroudis G, Zoumpanioti M, Brulet A, Ćirkovic Veličković T, Combet S, Nikolić M, Minić S. Exploring and strengthening the potential of R-phycocyanin from Nori flakes as a food colourant. Food Chem. 2023;426:136669. https://doi.org/10.1016/j.foodchem.2023.136669
  • Šunderić M, Gligorijević N, Milčić M, Minić S, Nedić O, Nikolić M. Phycocyanobilin is a new binding partner of human alpha-2-macroglobulin that protects the protein against oxidative stress. J Biomol Struct Dyn. 2023;17:1-11. https://doi.org/10.1080/07391102.2023.2248273
  • Platanic Arizanovic L, Gligorijevic N, Cvijetic I, Mijatovic A, Ristivojevic MK, Minic S, Kokic AN, Miljevic C, Nikolic M. Human Hemoglobin and Antipsychotics Clozapine, Ziprasidone and Sertindole: Friends or Foes? International Journal of Molecular Sciences. 2023:24(10):8921. https://doi.org/10.3390/ijms24108921
  • A. Simović, S. Combet, T. Ćirković-Veličković, M. Nikolić, S. Minić. Probing the stability of the food colourant R-phycoerythrin from dried Nori flakes. Food Chem. 2022; 374:131780. doi: 10.1016/j.foodchem.2021.131780 
  • N. Gligorijević, S. Minić, M. Radibratović, V. Papadimitriou, O. Nedić, T. Sotiroudis, M. Nikolić. Nutraceutical phycocyanobilin binding to catalase protects the pigment from oxidation without affecting catalytic activity. Spectrochim Acta A Mol Biomol Spectrosc. 2021;251:119483. doi: 10.1016/j.saa.2021.119483 
  • N. Gligorijević, T. Vasović, S. Lević, Č. Miljević, O. Nedić, M. Nikolić. Atypical antipsychotic clozapine binds fibrinogen and affects fibrin formation. Int J Biol Macromol. 2020;154:142-149. doi: 10.1016/j.ijbiomac.2020.03.119 
  • S. Minić, B. Annighöfer, A. Hélary, Dj. Hamdane, G. Hui Bon Hoa4, C. Loupiac, A. Brûlet, Sophie Combet. Effect of Ligands on HP-Induced Unfolding and Oligomerization of β-Lactoglobulin. Biophys J. 2020;119(11):2262-2274. doi: 10.1016/j.bpj.2020.10.019 
  • S. Minić, M. Milčić, D. Stanić-Vučinić, M. Radibratović, T. Sotiroudis, M. Nikolić, T. Ćirkovic Veličković. Phycocyanobilin, a bioactive tetrapyrrolic compound of blue-green alga Spirulina, binds with high affinity and competes with bilirubin for binding on human serum albumin. RSC Adv. 2015;5:61787-61798. doi: 10.1039/C5RA05534B 

Partners

Projects

Strengthening the potential of algal proteins for food colouring and fortification using high-pressure technology (PRESSION; No. ANSO-CR-PP-2021-01; 2022-2024.)

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Comprehensive platform for selecting and producing algal extracts for efficient serum albumin replacement in meat cultivation (ALG2MEAT; US Good Food Institute research grant project; 2023-2024.).

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Exploring the potential of algal-derived (chromo)peptides as serum replacement components for meat cultivation (PROMIS 2023)

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