Course code:
272H2		 Course name:
New Synthetic Methods

Academic year:

2023/2024.

Attendance requirements:

There are no requirements.

ECTS:

10

Study level:

doctoral academic studies

Study programs:

Chemistry: 1. year, winter semester, elective (E72H2) course

Chemistry: 1. year, winter semester, elective (E71H2) course

Chemistry: 2. year, winter semester, elective (E73H2) course

Chemistry: 2. year, winter semester, elective (E74H2) course

Teachers:

Radomir N. Saičić, Ph.D.
full professor, Faculty of Chemistry, Studentski trg 12-16, Beograd

Filip J. Bihelović, Ph.D.
associate professor, Faculty of Chemistry, Studentski trg 12-16, Beograd

Bojan Z. Vulović, Ph.D.
assistant professor, Faculty of Chemistry, Studentski trg 12-16, Beograd

Assistants:

—

Hours of instruction:

Weekly: five hours of lectures + three hours of study research work

Goals:

Students should get acquainted with novel developments in organic synthesis, which include: 1) New reactions; 2) New reagents and catalysts; 3) Modified conditions for conducting organic reactions; 4) Catalytic asymmetric synthesis; and 5) Domino reactions.

Outcome:

Capacity to independently select and apply optimal synthetic procedures in order to solve synthetic problems in the domain of research work and/or industrial application.

Teaching methods:

Lectures, seminal works.

Extracurricular activities:

—

Coursebooks:
  • R. N. Saicic: Synthesis of Complex Organic Molecules, notes for internal use, 2021.
  • I. Ojima: Catalytic Asymmetric Synthesis, Wiley VCH, N. Y., 2000. ISBN 0-471-29805-0
  • L. S. Hegedus: Transition Metals in the Synthesis of Complex Organic Molecules, University Science Books, Sausalito, California, 1999. ISBN 1-891389-04-1
  • J. Tsuji: Transition Metal Reagents and Catalysts, John Wiley & Sons, N. Y., 2000. ISBN: 0-471-56027-8

Additional material:

—

  Course activities and grading method

Lectures:

15 points (5 hours a week)

Syllabus:

  • Fundamentals of the reactivity of organotransition metal complexes;
  • Enantioselective hydrogenations;
  • Cross couplings;
  • The Heck reaction;
  • Alkene metathesis;
  • Reactions catalyzed by gold complexes;
  • Reactions catalyzed by cobalt complexes;
  • Enantioselective oxidations;
  • Organocatalysis;
  • Domino-reactions;
  • Solid supported synthesis;
  • Photoredox reactions.

Semester papers:

15 points

Oral exam:

70 points

Study research work:

0 points (3 hours a week)