Course code:
141B2		 Course name:
Bioinorganic Chemistry

Academic year:

2024/2025.

Attendance requirements:

There are no requirements.

ECTS:

8

Study level:

basic academic studies

Study program:

Biochemistry: 4. year, summer semester, elective (E17B2) course

Teacher:

Milica R. Milenkoviæ, Ph.D.
associate professor, Faculty of Chemistry, Studentski trg 12-16, Beograd

Assistants:

—

Hours of instruction:

Weekly: four hours of lectures + two hours of labwork (4+0+2)

Goals:

Within this course students are introduced to the fundamentals of bioinorganic chemistry, medicinal chemistry and biomimetic chemistry, with a special emphasis on the mechanisms of enzyme-catalyzed reactions.

Outcome:

Students will master the fundamentals of bioinorganic chemistry.

Teaching methods:

Lectures, tutorials, term papers, experimental exercises.

Extracurricular activities:

—

Coursebooks:

Main coursebooks:

  1. Ivano Bertini, Harry B. Gray, Edward I. Stiefel, Joan Selverstone Valentine: Biological Inorganic Chemistry, Structure and Reactivity, University Science Books, 2007.
  2. Robert R. Crichton: Biological Inorganic Chemistry, A New Introduction to Molecular Structure and Function, Elsevier, 2012.
  3. Wolfgang Kaim, Brigitte Schwederski, Axel Klein: Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life, An Introduction and Guide, Wiley, 2013.
  4. A. Messerschmidt, R. Huber, K. Wieghardt, T. Poulos: Handbook of Metalloproteins, John Wiley & Sons, Inc. 2001.
  5. Hermann Dugas: Bioorganic Chemistry, Springer, 1996.
  6. Dušan Sladić: Bioorganska hemija. Mehanizmi enzimskih reakcija
  7. Richard B. Silverman: The Organic Chemistry of Enzyme-Catalyzed Reactions, Academic Press, 2000.
  8. Gareth Thomas: Medicinal Chemistry: An Introduction, Wiley, 2007.
  9. Graham L. Patrick: An Introduction to Medicinal Chemistry, Oxford University Press, 2013.
  10. Donald Voet, Judith G. Voet: Biochemistry, 4th Edition, Wiley, 2011.
  11. Recent review and scientific papers dealing with metalloenzymes and enzyme mimetics.

Supplementary coursebooks:

  • Recent review and scientific papers in this field.

Additional material:

https://sites.chem.utoronto.ca/chemistry/coursenotes/GTM/tours.html

  Course activities and grading method

Lectures:

0 points (4 hours a week)

Labwork:

10 points (2 hours a week)

Semester papers:

20 points

Colloquia:

20 points

Written exam:

50 points